Metachronous Bilateral Vestibular Schwannomas

Mohamed Elsayed; Baptiste Hochet; Victor Renato Torres Lazo; Olivier Sterkers; Yann Nguyen; Ghizlene Lahlou; Michel Kalamarides

doi:10.1002/lary.28571

Metachronous Bilateral Vestibular Schwannomas

Mohamed Elsayed, Baptiste Hochet, Victor Renato Torres Lazo, Olivier Sterkers, Yann Nguyen, Ghizlene Lahlou, Michel Kalamarides

Departamento Académico de Cs. Fisiológicas

Research output: Contribution to journal › Article › peer-review

Abstract

Bilateral vestibular schwannoma (BVS) is the hallmark of neurofibromatosis type 2 (NF2), both of them being present at diagnosis. We report four cases of metachronous BVS, a contralateral intracanalicular vestibular schwannomas (VS) being visible 2 to 13 years after resection of a unilateral VS. NF2 workup was negative except in one case where two NF2 gene mutations were found in tumor analysis. These cases raise the questions of whether the contralateral VS occurred by chance and how to manage it on the only hearing ear. Otologists should be aware of this rare eventuality for decision making of the first unilateral VS. Laryngoscope, 131:E250–E254, 2021.

Original language	English
Pages (from-to)	E250-E254
Journal	Laryngoscope
Volume	131
Issue number	1
DOIs	https://doi.org/10.1002/lary.28571
State	Published - Jan 2021

Bibliographical note

Publisher Copyright:
© 2020 The American Laryngological, Rhinological and Otological Society, Inc.

Keywords

Bilateral vestibular schwannoma
metachronous benign tumors
neurofibromatosis type 2
sporadic vestibular schwannoma

Access to Document

10.1002/lary.28571

Cite this

@article{849cdf2e0c3344d58ddeeb118ae1501e,

title = "Metachronous Bilateral Vestibular Schwannomas",

abstract = "Bilateral vestibular schwannoma (BVS) is the hallmark of neurofibromatosis type 2 (NF2), both of them being present at diagnosis. We report four cases of metachronous BVS, a contralateral intracanalicular vestibular schwannomas (VS) being visible 2 to 13 years after resection of a unilateral VS. NF2 workup was negative except in one case where two NF2 gene mutations were found in tumor analysis. These cases raise the questions of whether the contralateral VS occurred by chance and how to manage it on the only hearing ear. Otologists should be aware of this rare eventuality for decision making of the first unilateral VS. Laryngoscope, 131:E250–E254, 2021.",

keywords = "Bilateral vestibular schwannoma, metachronous benign tumors, neurofibromatosis type 2, sporadic vestibular schwannoma",

author = "Mohamed Elsayed and Baptiste Hochet and {Torres Lazo}, {Victor Renato} and Olivier Sterkers and Yann Nguyen and Ghizlene Lahlou and Michel Kalamarides",

note = "Publisher Copyright: {\textcopyright} 2020 The American Laryngological, Rhinological and Otological Society, Inc.",

year = "2021",

month = jan,

doi = "10.1002/lary.28571",

language = "Ingl{\'e}s",

volume = "131",

pages = "E250--E254",

journal = "Laryngoscope",

issn = "0023-852X",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - Metachronous Bilateral Vestibular Schwannomas

AU - Elsayed, Mohamed

AU - Hochet, Baptiste

AU - Torres Lazo, Victor Renato

AU - Sterkers, Olivier

AU - Nguyen, Yann

AU - Lahlou, Ghizlene

AU - Kalamarides, Michel

PY - 2021/1

Y1 - 2021/1

N2 - Bilateral vestibular schwannoma (BVS) is the hallmark of neurofibromatosis type 2 (NF2), both of them being present at diagnosis. We report four cases of metachronous BVS, a contralateral intracanalicular vestibular schwannomas (VS) being visible 2 to 13 years after resection of a unilateral VS. NF2 workup was negative except in one case where two NF2 gene mutations were found in tumor analysis. These cases raise the questions of whether the contralateral VS occurred by chance and how to manage it on the only hearing ear. Otologists should be aware of this rare eventuality for decision making of the first unilateral VS. Laryngoscope, 131:E250–E254, 2021.

AB - Bilateral vestibular schwannoma (BVS) is the hallmark of neurofibromatosis type 2 (NF2), both of them being present at diagnosis. We report four cases of metachronous BVS, a contralateral intracanalicular vestibular schwannomas (VS) being visible 2 to 13 years after resection of a unilateral VS. NF2 workup was negative except in one case where two NF2 gene mutations were found in tumor analysis. These cases raise the questions of whether the contralateral VS occurred by chance and how to manage it on the only hearing ear. Otologists should be aware of this rare eventuality for decision making of the first unilateral VS. Laryngoscope, 131:E250–E254, 2021.

KW - Bilateral vestibular schwannoma

KW - metachronous benign tumors

KW - neurofibromatosis type 2

KW - sporadic vestibular schwannoma

UR - http://www.scopus.com/inward/record.url?scp=85079727112&partnerID=8YFLogxK

U2 - 10.1002/lary.28571

DO - 10.1002/lary.28571

M3 - Artículo

C2 - 32065398

AN - SCOPUS:85079727112

SN - 0023-852X

VL - 131

SP - E250-E254

JO - Laryngoscope

JF - Laryngoscope

IS - 1

ER -

Metachronous Bilateral Vestibular Schwannomas

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this