Pig as a large animal model for posterior fossa surgery in oto-neurosurgery: A cadaveric study

Mohamed Elsayed, Victor Renato Torres Lazo, Olivier Sterkers, Daniele Bernardeschi, Yann Nguyen

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


This study proposes a practical model for a new approach to the posterior fossa in common domestic pigs. Several surgical procedures can be simulated in the nonliving pig model, including soft tissue dissection, drilling of temporal bone, dural incision, access to the cerebellopontine angle, exposure of cranial nerves and drilling of the internal auditory canal. The pig model perfectly simulates standard otological and neurosurgical procedures, and we highlight the feasibility of our approach for further experiments in a living pig model with the possibility of reproducing the model for research on cranial nerves in pigs to study their electrophysiological behavior.

Original languageEnglish
Article numbere0212855
JournalPLoS ONE
Issue number2
StatePublished - Feb 2019
Externally publishedYes

Bibliographical note

Funding Information:
This work was supported by the Ministry of higher education, Mission sector, Egypt (http:// www.mohe-casm.edu.eg) and the Ministry of Scientific Research, Egypt to ME. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Publisher Copyright:
© 2019 Elsayed et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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